You can come to Yoo Yen Pen Sook by taxi but the best way to come here is going by airport real link Skytrain and get off Phaya Thai Station and change to BTS Skytrian. Going by BTS Skytrian for 4 stations and get off at Skytrian Saphan Khwai Station. Walk out from Exit 3 and go straight to the north about 100 meters, you can see thanacart bank and the alley on your left. Turn left to the alley and turn right at the first by way you can see the nice hostel on your right.