How to reach Castelmuzio: From Highway A1 exit Bettolle - Valdichiana. Take the Siena - Perugia motorway junction towards Siena and exit at Sinalunga. Follow the directions for Amorosa or Trequanda and continue for about 11 km until Castelmuzio. Just outside Castelmuzio, 100 meters from the inn, you will find ample free parking.