From Palermo airport (' Falcone Borsellino ') or Trapani irport , take the A29 motorway towards Palermo , exit Corso Calatafimi and continue for about 2 km to Corso Vittorio Emanuele and continue for 200 meters behind the Cathedral . From the Palermo's Central Station take the bus nr.109 and get off at the last stop ' Piazza Indipendenza'. Continue to Corso Vittorio Emanuele for around 300 meters to the Cathedral .